Indlela i-Optics kwi-Life Sciences eqinisa ngayo i-Precision Diagnostics kanye noCwaningo

Kwadalwa ngo 10.26, Kubuyekezwe ngo Ngokwamukisa

Indlela i-Optics KwezeSayensi Yempilo Eqinisa Ngayo Ukuxilonga Okunembile Nocwaningo

I-Optics empilweni nesayensi isisukile emaphethelweni omkhuba waselabhorethri yaya maphakathi nendawo yendlela abacwaningi ababona ngayo, abalinganisa ngayo, futhi abelapha ngayo izinhlelo zebhayoloji. Eminyakeni engamashumi amabili edlule, isibonakhulu sasiyithuluzi elizimele futhi i-spectrometer yayiyinto ethakazelisayo eboshelwe etafuleni; namuhla, izingxenye ezincane ze-optics zifakwe ngaphakathi kwabahlaziyi bokuxilonga, amarobhothi okuhlinza, izihlukanisi ze-DNA, namadivayisi okunakekela aseduze asuka aye emgodini womgcagco womguli. Umkhakha uhlangene eduze kwemisinga emithathu ehlangene: ihadiwe ye-optics eya ngokuya icwengeka, izindlela zokuthwebula ezinamandla, kanye nemigudu yokuhlaziya idatha ekhipha incazelo kuma-photon. Awukho kulemisinga osebenza ngaphandle kweminye, futhi awukho osebenza ngaphandle kwezingxenye ezethembekile ngaphansi. Ijubane lokutholakala ku-genomics, i-oncology, i-immunology, ne-neuroscience manje ngokwengxenye alikhawulwa ukucabanga kwebhayoloji kodwa izinga lokulethwa kokukhanya nokutholwa kokukhanya okutholakala kubakhi bamathuluzi. Yingakho i-optics empilweni nesayensi isiphenduke umkhakha wobunjiniyela wamasu esikhundleni semininingwane yezobuchwepheshe esekelayo.

Ukuhlangana kuyabonakala esigabeni ngasinye somsebenzi wocwaningo. Ukulungiswa kwesampula kuncike ekukhanyisweni okunembile kwezinhlelo ze-photoactivation ne-photobleaching; ukuphenywa kuncike emithonjeni eqinile yokukhanyisa nezihlungi ze-narrowband; ukutholwa kuncike ezinzwa ezingenamsindo kanye ne-high-transmission optics. Ngaleso sikhathi, ukuhunyushwa kwezempilo kudinga ukuthi konke lokhu kuhlale kukwazi ukumelana nokubulawa kwamagciwane, ukudlidliza, ukushintsha kokushisa, kanye neminyaka yokusebenza okuqhubekayo endaweni yesibhedlela. I-Honray Optics isebenza khona kanye kule nhlangano, ihlinzeka ngezakhiwo ze-optical ezinembile, ama-coatings, kanye nama-subsystems ahlanganisiwe kubathuthukisi bamathuluzi abasebenza kuzo zombili izimakethe zocwaningo nezezempilo. Ukuqonda indlela ukukhanya okuziphatha ngayo ngaphakathi kwesampula sezinto eziphilayo, nokuthi izingxenye ezakhiwe ngokucophelela zikugcina kanjani lokho kuziphatha, kuyisisekelo sakho konke okulandelayo kulesi sihloko.

I-Optics Njengesisekelo Sobuchwepheshe BeSayensi Yempilo

Ekugcineni, i-optics empilweni nesayensi iwukulawulwa okuhlelekile kokukhanya: ukukukhiqiza, ukukubumba, ukukudlulisa, ukukuhlunga, nokukuthola ngokunemba okwanele ukuba isignali yebhayoloji ihlukaniswe nomsindo. Ukukhanya kusebenzisana nezicubu ngokumuncwa, ukusakazeka, i-fluorescence, ukushintsha kwe-Raman, nokubambezeleka kwesigaba, futhi ngakunye kwalokhu kusebenzisana kuthwala ulwazi lokuxilonga. Ukuze kufundwe lolo lwazi, ithuluzi kufanele lilawule umkhawulo wesipikthiri, isimo se-polarization, izinga le-wavefront, nesikhathi ngokunakekela okungavamile. Isibonakhulu se-fluorescence esinesibuko se-dichroic esigcotshwe kabi sizovuza ukukhanya kwe-excitation endleleni yokuthola futhi sicekele phansi umehluko kungakhathaliseki ukuthi ikhamera ingcono kangakanani. I-flow cytometer ene-laser engazinzile izohamba ngamandla futhi ikhiqize idatha yabantu eshintshayo ukusuka ekusebenziseni kuya kokunye. Lokhu akuzona izinto ezikhathazayo ezingabonakali; yizimo zokwehluleka zansuku zonke ezinqunywa izinga lezingxenye.

Isikhala sohlelo lokusebenza sibanzi ngendlela emangalisayo. Ekuxilongeni kwamaseli, amasistimu okukhanya abala, ahlukanise ngezigaba, futhi akhombise uhlobo lwamaseli ngamazinga ezinkulungwane ezingamashumi amaningi ngomzuzwana, encike ezimpawini zokusakazeka kanye ne-fluorescence enemibala eminingi. Ekuthwebuleni izithombe, izinkundla ze-confocal, i-light-sheet, ne-super-resolution ziqhubekisela phambili ukucaca kuze kufike esikalini se-nanometer kuyilapho zifuna ukulawulwa okungcono nakakhulu kwe-aberration. Amasistimu okuqondisa ukuhlinzwa asebenzisa i-optical coherence tomography, ukulebula nge-fluorescence, kanye nokukhanya okuhlelekile ukusiza odokotela abahlinzayo ukuthi bahlukanise izicubu ezinempilo emingceleni yesimila ngesikhathi sangempela. Amathuluzi ocwaningo ahlanganisa lonke uhla, kusukela kuma-microplate readers nezitholi ze-capillary electrophoresis kuya kuma-optical tweezers namathuluzi okuthwebula izithombe ze-single-molecule. Ngayinye yalezi zinhlelo zokusebenza igcizelela ngendlela ehlukile ukudluliswa, umkhawulo womonakalo, ukuzinza kokushisa, noma ukunemba kwe-wavefront, futhi ngayinye ivuza abaklami abacacisa izingxenye ngokuhambisana ne-physics yangempela yokuhlolwa kwabo.

Okuhlanganisa lezi zinhlelo zokusebenza yisidingo esabiwe sokwenzeka kabusha. Ithuluzi lokuxilonga kufanele likhiqize impendulo efanayo ngoMsombuluko njengoba yenza ngoLwesihlanu, futhi inkundla yocwaningo kufanele ivumele imiphumela evela elabhorethri eyodwa ukuba iqhathaniswe nemiphumela evela kwelinye. Ukwenzeka kabusha kwezinto ezibonakalayo kuqala ngokufana kwezinto, ukubekezelelana okuqinile kobukhulu, izinto zokumboza ezincanyana ezihlala isikhathi eside, kanye nokusebenza okubhaliwe ngaphansi kwengcindezi yemvelo. I-Honray Optics ibhekana nalokhu ngokuklama nokwakha kwangaphakathi kwamalensi, ama-prism, izibuko, izihlungi, nama-waveplate, namakhono okumboza asuka ku-ultraviolet kuya ku-infrared. Abakhi bamathuluzi abathatha i-optics njengento ejwayelekile bavame ukuthola izindleko kamuva, lapho ukwehluleka kwensimu noma ukwehla kokulinganisa kudicilela phansi ukuthembela kwabasebenzisi. Ukuthatha i-optics njengengxenye yohlelo eklanyelwe kusukela ekuqaleni kuyindlela engcono kakhulu kwezomnotho, futhi iyindlela izinkampani ezihamba phambili zesayensi yempilo ezilandelayo manje.

Ukulawula Okuthuthukile Kwe-Spectral Ne-Temporal Emishinini Yesimanje

I-microscopy ye-fluorescence kanye ne-flow cytometry yizona zinto ezimbili eziyisisekelo sokuhlaziywa kwamaseli, futhi zombili ziphila noma zifa ngokugcinwa kwemithetho ye-spectral. Ku-microscopy ye-fluorescence, amabhendi e-excitation ne-emission avame ukuhlukaniswa ngamashumi amabili noma amashumi amathathu kuphela ama-nanometer, okusho ukuthi izihlungi ze-dichroic ne-emission kufanele zinikeze imiphetho eqondile, ukudluliswa okuphezulu ebhendini yokudlula, nokuvinjwa okujulile ngaphandle kwayo. Wonke ama-photon aphambukayo afinyelela kusitholi ngaphandle kokuvela ku-fluorophore anciphisa ububanzi be-dynamic futhi aphoqa izikhathi zokuchayeka ezinde, okubuye kwandise i-phototoxicity. Ukulawulwa kwesikhathi kubalulekile ngendlela efanayo nokulawulwa kwe-spectral, ngoba ama-fluorophore anezikhathi zokuphila ezihlukile futhi ngoba ukuthwebula kwamaseli aphilayo kudinga ukukhanyisa okuzinzile emahoreni amaningi. Umthombo we-LED noma we-laser okhanyayo ngamaphesenti ambalwa uzokwethula ama-artifact okungekho ukucubungula kwangemuva okungakwazi ukuwaqeda ngokuphelele.

I-flow cytometry ikhuphula izinga nakakhulu ngoba isebenza ngesivinini. Amaseli adlula endaweni yokuhlola ngama-microseconds, ngakho-ke uhlelo lwe-optical kufanele luqoqe ukukhanya okusakazekile nokukhishiwe okuningi ngangokunokwenzeka ngenkathi kugcinwa ukuhlukaniswa kwe-spectral okubukhali kuziteshi eziningi ze-detector. Amathuluzi esimanje avamise ukukala amapharamitha ayishumi kuya kwangamashumi amathathu ngasikhathi sinye, okwandisa izidingo zokuklanywa kwe-filter, ukufana kwe-dichroic coating, kanye ne-beam-shaping optics. Ukukhanyisa okunomsindo ophansi kubalulekile ngoba isilinganiso se-signal-to-noise sibeka umkhawulo wokuxazulula phakathi kwamaqembu amancane. I-Honray Optics isekela lolu hlobo lwemishini ngama-filter asebenza kahle kakhulu, ama-beam splitters anemba, kanye namalensi e-collimating ne-focusing enziwe ngokulingana okuqinile, futhi ithimba lobunjiniyela lenkampani lisebenza njalo namakhasimende ukuze lihambise ama-coating curves kuma-fluorophore panels athile esikhundleni sokuphoqa ingxenye ye-catalog ejwayelekile emsebenzini engaklanyelwanga wona.

Izingxenye Zokubona Eziguqukayo Zokuhlaziya Kwesikhathi Sangempela

Ukukhanya okumile kukodwa ngeke kukwazi ukusebenzela amathuluzi okufanele azivumelanise ngokushesha. Amathuluzi e-acousto-optic, ama-electro-optic modulator, kanye nezinqubo zokuskena ngokushesha zivumela imisebe ukuthi iqondiswe, ishintshwe, incishiswe, futhi ilolongwe ngezinga elingakwazi ukufinyelelwa yizinhlelo zemishini. Ku-confocal microscopy, izihlungi ezilungisekayo ze-acousto-optic zikhetha amaza okukhanyisa futhi zivale umsebe ngesikhathi sokubuyela emuva ukuze isampula lingakhanyiswa ngokungadingekile. Ekuhlolweni kwe-high-throughput, ukuqondiswa komsebe ngokushesha kuvumela indlela eyodwa yokukhanya ukuthi ibhekane nezitsha eziyizinkulungwane ngehora ngaphandle kokuhambisa isiteji sesampula. Ekuhlinzeni nge-laser kanye nezinhlelo zamehlo, ukulungiswa kulawula ukulethwa komthamo ngokunemba kwe-microsecond. Into efanayo ukuthi izinqumo zokukhanya zenziwa nge-elektroniki, okwenza ithuluzi lonke lisheshe, lithule, futhi lihleleke kalula kunomklamo wemishini kuphela.

Amasistimu anezinga eliphezulu lokusebenza azuza ngezindlela okulula ukuzibukela phansi. Ukuskena okusheshayo kunciphisa isikhathi isampula ngayinye esichitha ngaphansi kokukhanya, okugcina ukuphila kwamaseli aphilayo futhi kunciphise ukuphela kombala emasampuleni agxilile. Izindlela zomsebe ezihlelekayo zivumela ukuthi izivivinyo eziningi zifundwe ngokuhamba kanye esikhundleni sokulandelana kokutholwa. Ukushintsha kwe-elekthronikhi kuqeda ukudlidliza nokuguga okuhlupha izingxenye ezinyakazayo, kuthuthukisa kokubili ukuthembeka nempilo yesevisi. Konke lokhu kuncike ekusebenzeni okulindelekile kwezinto zokubona ezizungezile, ngoba i-modulator ihle kuphela njengomsebe ewumodulayo. Amalensi okugxilisa asezingeni eliphezulu, izinto zokubona ezidlulisayo ezingenalo ukuphambuka, kanye nezisekelo ezizinzile kunquma ukuthi uhlelo olusheshayo luyanemba futhi. Abaklami abahlanganisa izingxenye eziguqukayo nezinto zokubona ezingaguquki ezaziwa kahle bathola inzuzo ephelele kukho kokubili.

Ukuthwebula Ngeso Lokhozi Kwezokuxilonga Okungangeneli

I-Optical coherence tomography yashintsha i-ophthalmology ngokunikeza izigaba ezijulile ze-retina ngaphandle kokuthinta noma imisebe, futhi i-physics eyisisekelo manje isetshenziswa kude nangaphezulu kweso. Ama-endoscopic OCT probes akhombisa imithambo ye-coronary, i-gastrointestinal mucosa, kanye nezindonga zomgudu womoya. Amasistimu e-dermatological ahlela ukujula kwezilonda zesikhumba ukuze aqondise izinqumo ze-biopsy. Amapulatifomu e-dental kanye ne-intravascular asebenzisa imigomo efanayo ye-interferometric ngama-probe geometries ahlukene. Okwenze lokhu kwanda kwaba nokwenzeka kwakungeyona imigomo emisha ye-physics kodwa ubunjiniyela obungcono: imithombo yokukhanya ehlangene, ama-interferometers asekelwe ku-fiber, kanye nama-optical assemblies aqinile akwazi ukumelana nokugoba, ukubulawa kwamagciwane, kanye nokujikeleza kokushisa. Umkhuba kulo mkhakha awunakuphikwa, futhi ukhomba ekubeni okuncane kakhulu, ukuhlanganiswa kwe-fiber okujulile, kanye nokuqina okukhulu emkhakheni kunokuba kube nokunemba okulingana nelebhu egumbini elilawulwayo.

Ukuhlanganiswa kwe-fiber kudinga ukunakwa okukhethekile ngoba kushintsha imikhawulo yokuklama ngokuphelele. Lapho ukukhanya kuhamba ngaphakathi kwe-fiber ebhebhethekayo esikhundleni sendawo ekhululekile, ukuzinza kokuhambisana kuyathuthuka kodwa kuvela ukulahlekelwa okusha ngenxa yokungasebenzi kahle kokuxhumanisa, ukuncipha okubangelwa ukugoba, kanye nokubonakaliswa kwezixhumi. Izindawo zamehlo ezisemngceleni we-fiber kufanele zigcotshwe ukuze kuncishiswe ukubonakaliswa kwangemuva kuyilapho zimelana nemijikelezo yokuhlangana ephindaphindiwe. Izidingo zokuqina ziphusha ngasekugcotshweni okuqinile, okuhlala isikhathi eside kanye nezingxenye ezingaphansi eziqinile ngomshini ezigcina ukuhambisana phakathi namakhulu ezinkulungwane zamahora okusebenza. Lona yindawo lapho isipiliyoni se-Honray Optics kuma-optics anemba kanye nokugcotshwa kwefilimu encane kusekela ngqo abathuthukisi bemishini yezokwelapha, imikhiqizo yabo okufanele idlule ukuqinisekiswa okuqinile kokulawulwa bese isebenza ngokuthembekile ezandleni zodokotela abangenaso isineke sokulungiswa kabusha.

I-AI Nokuthwebula Ngekhompyutha Kuthuthukisa Idatha Ye-Optical

I-Artificial intelligence ishintshile lokho okungatholwa yizinsiza zokubona ezibonisa ngokukhanya kusuka ekukhanyeni ezikutholayo. Ama-algorithms okususa umsindo abuyisela izithombe ezitholakala ekuthathweni kwesithombe ngokukhanya okuphansi obekungayikulahlwa ngaphambili, amanethiwekhi e-deconvolution acijisa imiqulu efiphele, futhi amamodeli okuhlukanisa abona amaseli, ama-nucleus, nezakhiwo zezicubu ngesilinganiso esikhulu. Ekuxilongeni, izihlukanisi ze-machine-learning zifunda izimpawu ze-spectral nezici ze-morphological ukuze zikhombise okungajwayelekile ukuze kubuyekezwe ochwepheshe. Amasu okuthwebula izithombe ngekhompyutha afana ne-Fourier ptychography ne-lens-free holography ashintsha ubunkimbinkimbi bezingxenyekazi zokusebenza ngama-algorithms okwakha kabusha, okwenza kube nokwenzeka ukuthwebula izithombe ngesilinganiso esiphezulu ngemigqa yokubona elula futhi eshibhile. Zonke lezi zindlela zabelana ngokuncika okukodwa: zidinga amasignali okufaka ekhwalithi ephezulu, ngoba i-algorithm ayikwazi ukubuyisela ulwazi olungakaze luthathwe uhlelo lokubona ngokukhanya.

Ukuncika okunjalo yikho okwenza i-AI inganciphisi ukubaluleka kwe-optics empilweni nakwisayensi kodwa ikukhulise. Inethiwekhi yezinzwa eqeqeshwe kudatha enomsindo izokhiqiza ngokuzethemba izimpendulo ezingalungile, futhi imodeli eqeqeshwe kumsetshenziswa owodwa ingase ihluleke komunye umphumela wawo wokukhanya ohluke kancane. Ukusebenza kwe-optics okungaguquki kuzo zonke izinsiza kwenza amasethi edatha afaniswe futhi amamodeli adluliselwe, okuwumehluko phakathi kokufuna ukwazi kocwaningo nethuluzi lezempilo eliqinisekisiwe. Ukudluliswa okuphezulu, ukusakazeka okuphansi, ukukhiqizwa kwemibala okunembile, nokukhanya okuzinzile konke kuthuthukisa isignali efinyelela ku-algorithm. Abakhi bamathuluzi abatshala imali ekhwalithini ye-optics bathola ukuthi amapayipi abo e-AI ahlangana ngokushesha, asebenza kahle kakhulu, futhi adinga ukuqeqeshwa okuncane lapho izinguquko zehadiwe zenzeka.

Amasistimu Amancane E-Optical Ahlanganisiwe EzeSayensi Yempilo

Ukushintsha okubaluleke kakhulu endaweni yabahlinzeki ukusuka ekuthengiseni izingxenye ngazinye kuya ekulethweni kwama-subsystem okukhanya ahlanganisiwe. Eminyakeni eyishumi edlule, ithimba lamathuluzi lalizozithengela ngokwehlukana amalensi, izihlungi, nezinto zokubopha bese lizihlanganisa ngaphakathi. Namuhla, izikhathi eziqinile zokugcina, amathimba amancane onjiniyela, kanye nemibhalo eqinile yezomthetho kwenza leyo ndlela ibize kakhulu. Lokho amakhasimende akufunayo iyingxenye ehlanganisiwe efika iqondisiwe, ihloliwe, futhi ibhalwe phansi ngokuvumelana nesicaciso, ukuze inkampani yamathuluzi ikwazi ukugxila kumakhemikhali okuhlola, isofthiwe, nokuqinisekiswa komtholampilo. Ama-subsystem ahlanganisiwe futhi anciphisa ingozi yamaphutha okunqwabelana kokubekezelelana, ngoba umhlinzeki oyedwa ulawula zonke izixhumanisi kuqeqebana lokukhanya.

I-Honray Optics yakhe amakhono ayo ngokushintsha lokhu, ihlanganisa ukwenziwa kwezinto zokubona ngokunemba, ukukhiqizwa kwamaprism nezibuko, ukukhiqizwa kwama-waveplate, kanye nokugqunywa kwezinto zokubona okuthuthukile ngaphansi kophahla olulodwa. Inkampani isebenza endaweni engu-3,000-square-meter enezitifiketi zekhwalithi ezifanele amakhasimende ezokwelapha kanye nezimboni, futhi isebenzela izinhlelo ezihlanganisa amadivayisi ezokwelapha, amasistimu e-laser, kanye nemishini yezokuphepha. Izivakashi zingahlola uhla oluphelele lwemikhiqizo ku-Imikhiqizo ikhasi, buyekeza amakhono okukhiqiza ku- IMBONI YETHU ikhasi, futhi ufunde ngemvelaphi yenkampani ku- Mayelana Nathi ikhasi. Amaqembu afuna ukuxoxa ngomklamo othile angafinyelela iqembu lobunjiniyela ngqo nge- Uhlobo ikhasi lokuxhumana, kuyilapho i- Izindaba isigaba silandelela intuthuko yakamuva kumalensi okubona kanye nasekusetshenzisweni kwezokwelapha. Kusukela ku- IKHASI LASEKHAYA ikhasi linikeza abasha ukuqondisisa okusheshayo ngemigqa yomkhiqizo wenkampani kanye nemininingwane yefektri.

Isiphetho: Kungani i-Optics Ihlala Iyisisekelo Sokuthuthukiswa KweSayensi Yempilo

I-Optics empilweni nesayensi akusona isici sokusekela kodwa ingumshayeli oyinhloko walokho okulingisekayo, ngakho-ke walokho okwaziwayo. Yonke inqubekelaphambili ekuhlaziyeni kweseli elilodwa, yonke intuthuko ekutholeni umdlavuza kusenesikhathi, yonke isinyathelo esibheke ekuhlinzeni okuncane kakhulu kuncike ekufakeni ukukhanya kusampula nasekubuyiseni ulwazi ngokuthembeka. Amathuluzi azochaza ishumi leminyaka elizayo azoba mancane, ashesha, asebenza ngokuzenzakalela kakhulu, futhi athuthukiswe kakhulu ngokubala, futhi ngakunye kwalokho kuthambekela kwandisa esikhundleni sokunciphisa isidingo sekhwalithi ye-optical. Abahlinzeki bezingxenye abaqonda i-biology kanye ne-physics basendaweni yokusheshisa leyo nqubekelaphambili kakhulu. I-Honray Optics isebenza nabathuthukisi bamathuluzi emhlabeni wonke ukuletha ama-optics anemba, ama-coatings aqinile, nama-assemblies ahlanganisiwe agcina ukusebenza kwawo phakathi kokuqinisekiswa, ukusetshenziswa, kanye neminyaka yokusetshenziswa okuvamile. Amaqembu ahlela ipulatifomu entsha noma axazulula umkhawulo we-optical onenkani ayakhuthazwa ukuthi axhumane ne-Honray Optics futhi aqale ingxoxo yezobuchwepheshe mayelana nezidingo zawo ze-optical zesayensi yempilo.

Imibuzo Evame Ukubuzwa (FAQ)

Kusho ukuthini ngempela i-optics empilweni nakusayensi?

Ibinzana lichaza ukusetshenziswa kwemigomo nezingxenye ze-optics ocwaningweni lwebhayoloji, ukuxilongwa, kanye nokwelashwa. Lihlanganisa amalensi, izihlungi, izibuko, izinto zokumboza, kanye nemithombo yokukhanya ngaphakathi kwamathuluzi afana ne-microscope, i-flow cytometer, i-plate reader, kanye nezinhlelo ze-optical coherence tomography. Liphinde lihlanganise i-physics yendlela ukukhanya okusebenzisana ngayo nezicubu namaseli, kuhlanganise i-fluorescence, ukusakazeka, ukumuncwa, kanye nokushintsha kwesigaba. Ngokwendlela esebenzayo, i-optics kwezempilo nesayensi iwumkhakha wobunjiniyela oxhumanisa umbuzo webhayoloji nesiginali ye-optics ekwazi ukulinganiswa.

Kungani izinga le-optical libaluleke kangaka ku-fluorescence microscopy?

Amasignali e-fluorescence ngokwemvelo awakhanyi kahle, futhi umehluko phakathi kwesithombe esisebenzisekayo nesingasebenziseki uvame ukuncika ekutheni ukukhanya okungadingekile kokukhanyisa kufinyelela kangakanani kumtshina. Izibuko ze-dichroic zekhwalithi ephezulu nezihlungi zokukhanya okukhishwayo zivimba ngokujulile ukukhanya kokukhanyisa kuyilapho zidlulisa ukukhanya okukhishwayo ngempumelelo, okukhulisa umehluko futhi kuvumele izikhathi zokuvezwa ezimfushane. Izikhathi zokuvezwa ezimfushane zinciphisa i-photobleaching ne-phototoxicity, okubaluleke kakhulu emsebenzini wamaseli aphilayo. Imithombo yokukhanyisa ezinzile ibuye ivimbele ukushintshashintsha kwesikhathi sokukhanya phakathi nokuhlolwa kwesikhathi eside kwe-time-lapse. Ngokomsebenzi, ama-optics angcono asho idatha ehlanzekile namasampuli anempilo engcono.

Amathuluzi e-acousto-optic awathuthukisa kanjani ukuhlaziywa kwe-high-throughput?

Amathuluzi e-acousto-optic asebenzisa amagagasi omsindo ku-crystal ukuze aphambukise noma aguqule i-laser beam nge-elektroniki, nezikhathi zokushintsha ezikalwa ngama-microseconds. Ekuhloleni okuphezulu kwe-throughput screening kanye ne-flow cytometry, lokhu kuvumela i-beam ukuthi iqondiswe phakathi kwama-wells noma amashaneli ngokushesha okukhulu kunalokho i-motorized stage engakwenza. Ukulawula nge-elektroniki futhi kuqeda ukudlidliza nokuguga kwemishini okuhambisana nezingxenye ezinyakazayo, okuthuthukisa ukuthembeka ezikhathini ezinde zokusebenza. Ukuguqulwa okuhleliwe kwe-programmable kuvumela amathuluzi ukuthi acishe i-beam lapho kungekho kukalwa okwenziwayo, okwandisa ukuphila kwesampula. Umphumela uwukutholwa okusheshayo, ukuphathwa kwesampula okumnene, kanye namaphrothokholi e-assay aguquguqukayo.

Yimiphi imikhuba elolonga ukuthwebula kwezithombe zamehlo ukuze kutholakale izifo ngaphandle kokuhlinza?

Kunemikhuba emithathu ebusa. Okokuqala, amasistimu aya ngokuya aba mncane, esuka emishinini yaselabhorethri egibelela inqola eya emishinini ephathwayo kanye nemishina esekelwe ku-catheter. Okwesibili, ukuhlanganiswa kwe-fiber kuya ngokuya kujula, kuthatha indawo yezindlela ezikhululekile ngezinto eziqinile ze-fiber ezibekezelela ukugoba nokuhlanjululwa. Okwesithathu, izidingo zokuqina ziyakhula ngoba imishina kufanele isebenze ngokuthembekile emitholampilo nasemakamelweni okuhlinza ngaphandle kokulungiswa kabusha okuvamile. I-Optical coherence tomography iyisibonelo saleyo mikhuba yomithathu njengoba ikhula isuka ku-ophthalmology ingena ku-cardiology, dermatology, kanye ne-gastroenterology. Abahlinzeki abakwazi ukuletha ama-optics aqinile ane-coating kanye nezixhumanisi ze-fiber eziqinile babalulekile kulolu shintsho.

Ingabe ubuhlakani bokwenziwa bunciphisa isidingo sezinto zokubona zekhwalithi ephezulu?

Cha, kuyakhulisa. Amamodeli okufunda ngomshini angakwazi ukususa umsindo futhi ahlukanise izithombe, kodwa awakwazi ukubuyisa ulwazi uhlelo lwezokubona olungakaze luluthwebule, futhi angakhulisa ngokuzethemba izinto ezingamanga uma okokufaka kukubi. Amathuluzi anokusebenza kwezokubona okungaguquguquki akhiqiza amasethi edatha aqhathanisekayo kuzo zonke izindawo, okwenza amamodeli adluliseke kalula futhi aqinisekiswe kalula. Ukubuyekezwa okulawulayo kwezokuxilonga okusekelwe ku-AI nakho kudinga ukusebenza kwengqalasizinda okubhaliwe, okuhlanganisa ukuzinza kwe-spectral namandla. Ngakho-ke ukutshala imali kuma-optics kwenza amapayipi e-AI ahlangane ngokushesha futhi asebenze kahle kuzo zonke izinguqulo zezingqalasizinda.

Yini i-optical subsystem ehlanganisiwe futhi kungani ibalulekile?

I-subsystem yamehlo ehlanganisiwe iyingxenye ehlelwe kusengaphambili, ehlolwe kusengaphambili yamalensi, izihlungi, izibuko, nezinto zokugxilisa ezilethwa njengeyunithi eyodwa ngokuvumelana nencazelo ebhaliwe. Kubalulekile ngoba amaqembu ezinsimbi abhekana nezikhathi zokuthuthukisa ezimfushane kanye nemibhalo yezomthetho eqinile kunanini ngaphambili. Ukuhlanganisa izingxenye eziningi ezincane ngaphakathi kwinkampani kuletha ingozi yokunqwabelana kwemikhawulo futhi kudla isikhathi sobunjiniyela ebesingasetshenziswa kumakhemistri yokuhlola kanye nesofthiwe. Umhlinzeki oyedwa olawula zonke izixhumanisi zamehlo angasiqinisekisa ukusebenza kusukela ekupheleni kuya ekupheleni. Le ndlela futhi yenza kube lula ukulawula izinguquko kanye nokuhlela ukuhlinzekwa kwesikhathi eside.

I-Honray Optics isekela kanjani abathuthukisi bezinsimbi zesayensi yempilo?

I-Honray Optics iklama futhi ikhiqize izinto zokukhanya ezinemba kakhulu ezihlanganisa amalensi, amaprism, izibuko, izihlungi, nama-waveplate, kanye nezingubo ezithuthukisiwe zefilimu emincane kusukela ku-ultraviolet kuya ku-infrared. Inkampani isebenza endaweni engu-3,000-square-meter enezitifiketi zekhwalithi ezifanele amakhasimende ezokwelapha nezimboni futhi isebenzela izinhlelo zokusebenza kumadivayisi ezokwelapha, amasistimu e-laser, nemishini yezokuphepha. Ithimba layo lobunjiniyela lisebenza namakhasimende ukuze lihambise amajika ezingubo nokubekezelela kumaphaneli athile e-fluorophore nezakhiwo zamathuluzi. Ulwazi oluningiliziwe lwemikhiqizo lutholakala kumakhasi e-Products kanye ne-OUR FACTORY enkampani, futhi izingxoxo zobuchwepheshe zingaqalwa ngekhasi lokuxhumana.

Yimiphi imininingwane yokumboza okufanele ngixoxe ngayo nomhlinzeki wezinto zokubona?

Qala ngobubanzi be-spectral obuthakaselayo kanye namazinga adingekayo okudlulisa nokuvimbela kuwo wonke ama-wavelength, ngoba lawa anquma umndeni wokuklama kwe-coating. Cacisa i-engeli yokungena kanye nokubekezelela kwayo, ngoba ukusebenza kwe-coating kushintsha nge-engeli futhi amathuluzi awavamile ukukhanyisa ngenani eliqondile elibekiwe. Xoxa nge-laser damage threshold uma kukhona imithombo ye-pulsed, kanye nezidingo zokuqina kwemvelo ezifana nomswakama, inkungu yetshe, nemijikelezo yokuhlanza. Ekugcineni, buza ngokuvumelana kwe-batch-to-batch nokuthi kuqinisekiswa kanjani, ngoba ukulinganiswa kwethuluzi kuncike ekutheni ama-coating aziphatha ngendlela efanayo kuzo zonke izinhlobo zokukhiqiza.

Ingabe izinto zokubona kwezempilo nesayensi kungenzeka zithuthuke kanjani emashumini eminyaka ezayo?

Lindela ukuncipha okwengeziwe, ngemisebenzi eminingi yokukhanya ihamba iya emiculweni, amasekhethi ahlanganisiwe e-photonic, namakhathriji alahlwayo okuhlolwa kwe-point-of-care. Lindela ukuxhumana okuqinile phakathi kwehardware nokubala, lapho ama-algorithms okwakha kabusha aklanywa kanye nohlelo lokukhanya esikhundleni sokwengezwa kamuva. Lindela isidingo esikhulayo sezilinganiso ze-spectral ezihlanganisiwe njengoba amaphaneli ama-biomarker ekhula. Lindela ukuhlolwa okulawulayo kokusebenza kokukhanya ukukhula kanye nokwamukelwa kwezempilo kokuxilongwa okusizwa yi-AI. Kuzo zombili izimo, imfuneko eyisisekelo iyafana: ukukhanya okuzinzile, okwaziwa kahle, nokuhlala isikhathi eside okuvumela ibhayoloji ukuthi ilinganiswe ngokuzethemba.

Jiangsu Honray Photoelectric Technology Co., Ltd.

Umschlag Hotline

Ucingo: +86-527-82898278

Imeyili：sales@honrayoptic.com

Feksi: +86-527-82898278

Ikheli：Isakhiwo 5, Ipaki Yezimboni Zokusebenza Nezokwakha, Isifunda iSucheng, Idolobha iSuqian, Jiangsu, China 223800